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Komodo dragon blood could help in AMR fight
komodo dragon
Komodo dragon saliva contains at least 57 species of bacteria that are thought to help kill their prey, but the Komodo itself appears to be resistant to the bacteria.
Scientists identify antimicrobial activity in lizard’s blood

Antimicrobial substances discovered in the blood of Komodo dragons could help with the development of new drugs for treating antibiotic resistant infections, scientists say.

A study published in the Journal of Proteome Research describes antimicrobial protein fragments that appear to help the lizards resist deadly infections.

Komodo dragon saliva contains at least 57 species of bacteria that are thought to help kill their prey, but the Komodo itself appears to be resistant to the bacteria.

Researchers from the College of Science at George Mason University identified and sequenced 48 potential cationic antimicrobial peptides (CAMPs) - an essential part of the innate immune system - in the blood of Komodo dragons. All but one of these were derived from histone proteins, which are known to have antimicrobial activities.

Eight were synthesised and tested against Pseudomonas aeruginosa and Staphylococcus aureus. Seven out of eight showed significant potency against both bacteria and the eighth was only effective against P. aeruginosa. The researchers conclude that Komodo blood plasma contains a host of potentially viable antimicrobial peptides that could lead to new treatments.

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FIVP announces third series of Practice Matters

News Story 1
 The Federation of Independent Veterinary practices (FIVP) has announced a third season of its podcast, Practice Matters.

Hosted by Ian Wolstenholme, series three will focus on the Competition and Markets Authority (CMA) investigation, including a discussion about some of the expected impacts on independent veterinary colleagues.

Episode one launches on 13th January with guests Drs David Reader and Scott Summers, who will draw on their research into the CMA investigation and provide insights into themes such as transparency, pricing and consumer trust.

Ian Wolstenholme said: "In its third series, we will try and hone in on what the changes will mean in reality for independent practices with advice and guidance on implementation and delivery, drawing on the experience of our own team and other experts in the profession. Hope you can join us soon!" 

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News Shorts
Survey seeks ruminant sector views on antimicrobial stewardship

A new survey is seeking views of people working in the UK ruminant sector on how to tackle the challenge of demonstrating responsible antibiotic stewardship.

Forming part of a wider, collaborative initiative, the results will help identify the types of data available so that challenges with data collection can be better understood and addressed.

Anyone working in the UK farming sector, including vets and farmers,is encouraged to complete the survey, which is available at app.onlinesurveys.jisc.ac.uk