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Researchers develop oral gel form of dexmedetomidine
Dogs given the dexmedetomidine gel displayed fewer signs of fear and anxiety than dogs in the placebo group.

Treatment reduces signs of fear and anxiety in dogs

Researchers have developed an oral gel form of dexmedetomidine that may be given by dog owners at home.

A study published in Veterinary Record concludes that the gel “significantly reduced behaviours related to fear and anxiety over time, and the overall effect and success of treatment were found superior to placebo.”

It adds that the dose used was “safe and devoid of any significant clinical sedative effect”. Furthermore, the new form of administration was found by owners to be easy to use across the range of dogs tested.

The innovation, developed by Orion Parma, is now available as a treatment on prescription.

In the study, researchers administered the gel or an identical placebo to 182 dogs with a history of acute anxiety and fear associated with fireworks noise. The experiment took place on New Years’ Eve 2012 and assessed the overall treatment effect in addition to signs and extent of anxiety and fear.

The study reports a higher proportion of dogs had a good or excellent treatment effect in the dexmedetomidine group (72 per cent) than in the placebo group (37 per cent). This means that the dogs did not show any signs of fear and anxiety, or the signs were mild and temporary.

It also reports that dogs given the dexmedetomidine gel displayed fewer signs of fear and anxiety than dogs in the placebo group, including panting, trembling and growling.

While the gel was found by owners to be easy to apply, the authors are reminding vets of the importance of instructing clients carefully on the correct use of new medications. They emphasise that a personalised treatment plan should be set up for every patient covering all appropriate treatment options.

The study has won this year’s Veterinary Record Impact Award for research that is considered likely to have the most significant practical impact by the journal’s research team. It was selected from some 150 papers published by Veterinary Record last year ‘due to its highly practical outcome for an issue often seen by vets in small animal practice’.

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Vets launch new podcast for pet owners

News Story 1
 Two independent vets have launched a podcast to help owners strengthen their bond with pets. Dr Maggie Roberts and Dr Vanessa Howie, who have worked in both veterinary practice and major charities, are keen to use their experience to enable people to give pets a better life.

The venture, called Vets Talking Pets, provides advice and information on a range of topics, including how to select a suitable pet, where to obtain them and how to get the best out of your vet. Maggie and Vanessa will also discuss sensitive subjects, including end-of-life care, raw food diets and the cost of veterinary care.

The podcast can be found on all the usual podcast sites, including Podbean, Apple, Amazon Music and YouTube. 

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News Shorts
VMD issues guidance on AVM-GSL packaging

The Veterinary Medicines Directorate (VMD) has shared advice on its requirements for medicines considered AVM-GSL.

The guidance explains the information that should be on the outer package, and sets out the typical maximum pack size for an AVM-GSL product. It also describes the user-friendly language, structure and phrases required on packaging and product leaflets.

AVM-GSL products do not require discussion between the purchaser and a veterinary professional. This means that clear product information is needed to support sales choices.

The information will be useful for submitting new products to the AVM-GSL category and lowering the distribution category of products from NFA-VPS to AVM-GSL.

The VMD's guidance can be accessed here.