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Vaccine offers hope in fight against major chicken disease
The recombinant vaccines have potential to be more cost-effective and respond to emerging new virus strains.
Researchers test effectiveness of recombinant virus vaccine

Researchers have developed a new vaccine strategy that could help chickens in the fight against infectious bronchitis.

Current vaccines that protect against infectious bronchitis guard against some strains of the virus, but not others. Scientists believe these failures are associated with differences in the spike protein - the protein which enables the virus to attach to and enter cells - between strains of the virus.

Writing in the Journal Of Virology, researchers describe how they tested a new approach using a specialist type of vaccine, known as recombinant virus vaccine. These vaccines use harmless or weak versions of a virus or bacteria to introduce microbes into cells into the body.

The team used recombinant viruses with different spike proteins as vaccines to build two versions of a harmless virus. They found that the vaccine offered partial protection against infectious bronchitis virus, but further research is needed to develop a more robust vaccine.

Researchers say the recombinant vaccines have potential to be more cost-effective and respond to emerging new virus strains. The next step will be to develop a vaccine that remains harmless but induces a stronger immune response.

Professor Lonneke Vervelde, who led the study at the University’s Roslin Institute, said: “There is a real need to develop new vaccines against infectious bronchitis that protect against multiple strains and offer rapid responses. We are trying to make a vaccine that offers broad protection, but further research is needed to develop a more robust vaccine.”

Dr Erica Bickerton at the Pirbright Institute, who also took part in the study, said: “Our research hopes to develop more cost-effective and efficient commercial vaccines that are capable of protecting chickens against this serious disease.”

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here. 

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.