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Scientists discover new ‘jumping’ superbug gene
“In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die.”
mcr-9 can cause resistance to colistin 

US food scientists have discovered mcr-9, a new ‘jumping gene’ that can cause resistance to the last resort antibiotic colistin.

Cornell University researchers found mcr-9 in the genome of a strain of salmonella. To their surprise, the salmonella strain did not show colistin resistance.

However, when the gene was inserted into a non-pathogenic strain of E coli, researchers were able to ‘turn on’ mcr-9, making the strain resistant to colistin.

The findings have been published in the journal Mbio.

Co-lead author Laura Carroll said: “When we originally tested the salmonella isolate and found that it wasn’t resistant to colistin, we were perplexed. But when [co-lead author Ahmed Gabella] cloned it into an E. coli host, he was able to find that the gene could confer resistance to colistin.”

Commenting on the findings, Professor Martin Wiedmann said: “In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die.”

mcr-9 is the latest in a string of ‘mobilised colistin-resistance genes’ first discovered in 2015.

The National Centre for Biotechnology Information added details of the new gene to its database, so that it can be used to identify the gene in bacteria isolated from food and people.

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RUMA CA&E extends survey deadline

News Story 1
 RUMA CA&E has extended the deadline for its online survey into vaccine availability.

Vets, SQPs, retailers and wholesalers will now have until Friday, 26 September at 5pm to submit their response.

The survey aims to further understanding into the vaccine supply challenges faced by the sector. It will also consider the short and long term impacts of disruption issues.

Insights are anonymous, and will be shared with industry stakeholders and government bodies.

The survey can be accessed here

Click here for more...
News Shorts
Dechra launches checklist for veterinary sustainability

Global animal health specialist Dechra has announced the world's first Veterinary Green Theatre Checklist (VGTC) to help make surgery more sustainable.

Endorsed by leading veterinary organisations, including the BEVA, BVNA and RCVS Knowledge, the checklist is designed to reduce the environmental footprint of veterinary care, while supporting better animal health outcomes.

The checklist was launched at the World Congress of Veterinary Anaesthesia and Analgesia in Paris and will be followed by an internal training and awareness campaign. For more information, visit dechra.com