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Painkilling black mamba snake
Image: George Grall
Deadly snake venom could form strong painkiller

According to a study by french scientists, the venom of the black mamba snake could help to form a painkiller as powerful as morphine.

The black mamba snake, which derives from Africa, is one of the world's fastest and most venomous. It is a compound found in their venom, called mambalgins, which gives pain relief when isolated.

The mambalgins are expected to have no side effects in humans, making it a potential replacement for morphine, which is addictive and can cause headaches, vomiting and muscle-twitching, amongst other conditions.

The study was published in the Nature journal, following tests on mice that showed mambalgins block the central and peripheral nervous system's acid-sensing ion channels (ASICs), effectively giving pain relief.

Herpetologist and toxicologist, Zolan Takacs, said: "Animal venom toxins have a solid success rate [becoming] major drugs. There is no question this will continue, as the vast majority of toxins remain unexplored."

Study leader, Anne Baron, of the Institute of Molecular and Cellular Pharmacology in France, said: "It's remarkable that this was made possible from the deadly venom of one of the most venomous snakes."

However, Takacs added: "To develop a new drug you need 10 to 15 years hundreds of millions of dollars, and you still have no guarantees". 

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RUMA CA&E extends survey deadline

News Story 1
 RUMA CA&E has extended the deadline for its online survey into vaccine availability.

Vets, SQPs, retailers and wholesalers will now have until Friday, 26 September at 5pm to submit their response.

The survey aims to further understanding into the vaccine supply challenges faced by the sector. It will also consider the short and long term impacts of disruption issues.

Insights are anonymous, and will be shared with industry stakeholders and government bodies.

The survey can be accessed here

Click here for more...
News Shorts
Dechra launches checklist for veterinary sustainability

Global animal health specialist Dechra has announced the world's first Veterinary Green Theatre Checklist (VGTC) to help make surgery more sustainable.

Endorsed by leading veterinary organisations, including the BEVA, BVNA and RCVS Knowledge, the checklist is designed to reduce the environmental footprint of veterinary care, while supporting better animal health outcomes.

The checklist was launched at the World Congress of Veterinary Anaesthesia and Analgesia in Paris and will be followed by an internal training and awareness campaign. For more information, visit dechra.com