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Vaccine for foot and mouth in five years, say researchers
Scientists hope to produce vaccine by end of five-year project

Leading research scientists have said they are confident a vaccine for foot-and-mouth disease (FMD) will be produced in the next five years.

Researchers from the Pirbright Institute and the universities of St Andrews, Leeds, Edinburgh and Dundee are working on a five-year project to form an effective vaccine for FMD type-O - the serotype that caused the 2001 UK outbreak.

The project, which hopes for a vaccine with improved responses, reduced need for revaccination, and eventually the development of a weapon against all known strains of the disease, has been part-funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

Terry Jackson, team leader on the FMD project at Pirbright, said: "The significant thing is that the universities can use sub-genomic replicons. These replicons don't produce infectious virus, so they are perfectly safe to work on outside of our containment facility. The universities now have permission to use them and at the end of this we would be very disappointed if we did not have a vaccine using the live unattenuated virus."

The 2001 FMD virus outbreak lead to the deaths of seven million sheep and cattle, and was estimated to have cost the British economy around £8b.

Dr Jackson added: "Success would be massive. A lot of people who work at Pirbright would love to leave a legacy; we would love to leave behind something and say we made a difference."

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.